Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19667710 | 1.00 | ESR2 (0.46) | ESR2NR1H2ADORA1DPP4MAPT | |
| SCHEMBL29523288 | 0.87 | ESR2 (0.43) | ESR2NR1H2ADORA1DPP4MAPT | |
| SCHEMBL23897065 | 0.87 | ESR2 (0.46) | ESR2NR1H2ADORA1DPP4MAPT | |
| SCHEMBL22787601 | 0.87 | ESR2 (0.43) | ESR2NR1H2ADORA1DPP4MAPT | |
| SCHEMBL19679214 | 0.85 | ESR2 (0.50) | ESR2NR1H2ADORA1DPP4MAPT | |
| SCHEMBL19679216 | 0.84 | ESR2 (0.49) | ESR2NR1H2ADORA1DPP4MAPT | |
| SCHEMBL19667592 | 0.84 | ESR2 (0.45) | ESR2NR1H2ADORA1DPP4MAPT | |
| SCHEMBL30207854 | 0.84 | ESR2 (0.45) | ESR2NR1H2ADORA1DPP4MAPT | |
| SCHEMBL19679219 | 0.83 | ESR2 (0.48) | ESR2NR1H2ADORA1DPP4MAPT | |
| SCHEMBL19679218 | 0.83 | ESR2 (0.51) | ESR2NR1H2ADORA1DPP4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026094-B | PRMT5 inhibitors | 印度鲁宾有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-114026094-A | PRMT5 inhibitor | 印度鲁宾有限公司 | 2022-02-08 | — | — | CN | disclosed |