Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.83 |
| ▸ | S100A4 | P26447 | 2/20 | 0.67 |
| ▸ | BCL2 | P10415 | 2/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | APAF1 | O14727 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GALK1 | P51570 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523603 | 1.00 | PTPRC (0.83) | PTPRCS100A4BCL2MCL1MAPK1 | |
| SCHEMBL5273079 | 1.00 | PTPRC (0.83) | PTPRCS100A4BCL2MCL1MAPK1 | |
| SCHEMBL29827415 | 0.95 | PTPRC (0.91) | PTPRCS100A4BCL2MCL1MAPK1 | |
| SCHEMBL3948979 | 0.95 | PTPRC (0.91) | PTPRCS100A4BCL2MCL1MAPK1 | |
| SCHEMBL824162 | 0.95 | PTPRC (0.91) | PTPRCS100A4BCL2MCL1MAPK1 | |
| SCHEMBL29689751 | 0.95 | PTPRC (0.91) | PTPRCS100A4BCL2MCL1MAPK1 | |
| SCHEMBL391353 | 0.93 | PTPRC (0.87) | PTPRCS100A4BCL2MCL1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL28061163 | 0.91 | PTPRC (0.83) | PTPRCS100A4BCL2MCL1MAPK1 | |
| SCHEMBL30987852 | 0.91 | PTPRC (1.00) | PTPRCS100A4BCL2MCL1MAPK1 | |
| SCHEMBL6259656 | 0.91 | PTPRC (1.00) | PTPRCS100A4BCL2MCL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022186645-A1 | HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER | 엘티소재주식회사 | 2022-09-09 | — | — | WO | disclosed |
| WO-2022066774-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |