Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536648 | 1.00 | CCNT1 (0.41) | CCNT1CDK9NR1H2NR1H3AGTR2 | |
| SCHEMBL29889444 | 0.99 | CCNT1 (0.41) | CCNT1CDK9NR1H2NR1H3AGTR2 | |
| SCHEMBL4309208 | 0.99 | CCNT1 (0.41) | CCNT1CDK9NR1H2NR1H3AGTR2 | |
| SCHEMBL4309204 | 0.99 | CCNT1 (0.41) | CCNT1CDK9NR1H2NR1H3AGTR2 | |
| SCHEMBL14915300 | 0.88 | USP2 (0.44) | CCNT1CDK9NR1H2NR1H3AGTR2 | |
| SCHEMBL15397259 | 0.88 | USP2 (0.44) | CCNT1CDK9NR1H2NR1H3AGTR2 | |
| SCHEMBL22333707 | 0.87 | HSD17B10 (0.41) | NR1H2NR1H3ALDH1A1FKBP1APTPN1 | |
| SCHEMBL4316869 | 0.87 | CCNT1 (0.40) | CCNT1CDK9NR1H2NR1H3AGTR2 | |
| SCHEMBL4316868 | 0.87 | CCNT1 (0.40) | CCNT1CDK9NR1H2NR1H3AGTR2 | |
| SCHEMBL21950735 | 0.86 | CCNT1 (0.41) | CCNT1CDK9NR1H2NR1H3AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2022066774-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |