Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.61 |
| ▸ | GRIN1 | Q05586 | 19/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22774536 | 1.00 | GRIN2B (0.61) | GRIN2BGRIN1 | |
| SCHEMBL22774532 | 0.81 | GRIN1 (0.57) | GRIN2BGRIN1 | |
| SCHEMBL22774432 | 0.81 | GRIN1 (0.63) | GRIN2BGRIN1 | |
| SCHEMBL22774666 | 0.81 | GRIN1 (0.69) | GRIN2BGRIN1 | |
| SCHEMBL22774946 | 0.78 | GRIN2B (0.65) | GRIN2BGRIN1 | |
| SCHEMBL22774316 | 0.76 | GRIN1 (1.00) | GRIN2BGRIN1 | |
| SCHEMBL22774465 | 0.75 | GRIN1 (0.62) | GRIN2BGRIN1 | |
| SCHEMBL22774340 | 0.75 | GRIN1 (0.69) | GRIN2BGRIN1 | |
| SCHEMBL22516866 | 0.73 | GRIN1 (0.54) | GRIN2BGRIN1 | |
| SCHEMBL22774526 | 0.73 | GRIN1 (0.57) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3982958-A1 | SUBSTITUTED HETEROAROMATIC PYRAZOLO-PYRIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | disclosed |