Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 20/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26970262 | 0.93 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL29526134 | 0.93 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL29526518 | 0.90 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL29526269 | 0.90 | MAP4K1 (0.87) | MAP4K1 | |
| SCHEMBL29525815 | 0.90 | MAP4K1 (0.91) | MAP4K1 | |
| SCHEMBL26970358 | 0.90 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL29525887 | 0.90 | MAP4K1 (0.90) | MAP4K1 | |
| SCHEMBL30689931 | 0.89 | MAP4K1 (0.86) | MAP4K1 | |
| SCHEMBL29525897 | 0.89 | MAP4K1 (0.86) | MAP4K1 | |
| SCHEMBL29527158 | 0.89 | MAP4K1 (0.85) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240362-A1 | DIAMINOPYRIMIDINE CARBOXAMIDE INHIBITORS OF HPK1 | Merck Sharp & Dohme LLC (US) | 2023-09-13 | — | — | EP | claimed |
| WO-2022098809-A1 | DIAMINOPYRIMIDINE CARBOXAMIDE INHIBITORS OF HPK1 | MERCK SHARP & DOHME CORP. (US) | 2022-05-12 | — | — | WO | claimed |
| EP-4240362-A1 | DIAMINOPYRIMIDINE CARBOXAMIDE INHIBITORS OF HPK1 | Merck Sharp & Dohme LLC (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022098809-A1 | DIAMINOPYRIMIDINE CARBOXAMIDE INHIBITORS OF HPK1 | MERCK SHARP & DOHME CORP. (US) | 2022-05-12 | — | — | WO | disclosed |