Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.73 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.73 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | IL1B | P01584 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668307 | 1.00 | CRBN (0.73) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL28667428 | 0.93 | CRBN (0.73) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL29528664 | 0.93 | CRBN (0.73) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL1399131 | 0.85 | CRBN (1.00) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL1398958 | 0.85 | CRBN (1.00) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL31741887 | 0.85 | CRBN (1.00) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL776766 | 0.85 | CRBN (1.00) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL1398905 | 0.82 | CRBN (0.67) | CRBNDDB1 | |
| SCHEMBL28655559 | 0.81 | CRBN (0.71) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL29528415 | 0.81 | CRBN (0.71) | CRBNDDB1IKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480520-B | Isoquinoline-1, 3(2H, 4H) -diketone derivative and application thereof | 吉林大学 | 2022-05-13 | — | — | CN | disclosed |