Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MDM4 | O15151 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178804 | 1.00 | KMT2A (0.60) | KMT2AMDM4TP53TLR2MDM2 | |
| SCHEMBL3487948 | 1.00 | KMT2A (0.60) | KMT2AMDM4TP53TLR2MDM2 | |
| SCHEMBL29401303 | 1.00 | KMT2A (0.60) | KMT2AMDM4TP53TLR2MDM2 | |
| SCHEMBL178805 | 1.00 | KMT2A (0.60) | KMT2AMDM4TP53TLR2MDM2 | |
| SCHEMBL3197099 | 0.94 | MDM2 (0.54) | KMT2AMDM4TP53TLR2MDM2 | |
| SCHEMBL29398472 | 0.93 | KMT2A (0.54) | KMT2AMDM4TP53TLR2MDM2 | |
| SCHEMBL29401297 | 0.93 | KMT2A (0.54) | KMT2AMDM4TP53TLR2MDM2 | |
| SCHEMBL20556494 | 0.93 | KMT2A (0.54) | KMT2AMDM4TP53TLR2MDM2 | |
| SCHEMBL20556492 | 0.93 | KMT2A (0.54) | KMT2AMDM4TP53TLR2MDM2 | |
| SCHEMBL178808 | 0.93 | KMT2A (0.54) | KMT2AMDM4TP53TLR2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946363-A2 | GLUCOSE SENSITIVE INSULIN DERIVATIVES | Novo Nordisk A/S (DK) | 2022-02-09 | — | — | EP | disclosed |