Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400615 | 1.00 | NOTUM (0.49) | NOTUMTTRMAPTMEN1KMT2A | |
| SCHEMBL29528597 | 0.81 | NOTUM (0.69) | NOTUMMAPTMEN1KMT2AHTT | |
| SCHEMBL22400332 | 0.81 | NOTUM (0.69) | NOTUMMAPTMEN1KMT2AHTT | |
| SCHEMBL1071876 | 0.80 | TTR (0.62) | NOTUMTTRMAPTKMT2ATPMT | |
| SCHEMBL26047383 | 0.80 | TPMT (0.42) | NOTUMMAPTMEN1KMT2AHTT | |
| SCHEMBL3310108 | 0.80 | TTR (0.48) | NOTUMTTRMAPTMEN1KMT2A | |
| SCHEMBL23699555 | 0.79 | TTR (0.52) | NOTUMTTRMAPTKMT2ATPMT | |
| Hydrochloric Acid SCHEMBL11632990 | 0.79 | TTR (0.47) | NOTUMTTRMAPTMEN1KMT2A | |
| SCHEMBL16528303 | 0.76 | TTR (0.44) | NOTUMTTRMAPTMEN1KMT2A | |
| SCHEMBL22400336 | 0.76 | TTR (0.44) | NOTUMTTRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746849-A1 | PHARMACEUTICAL COMPOSITIONS OF INSULIN DERIVATIVES | Novo Nordisk A/S (DK) | 2026-05-27 | — | — | EP | disclosed |
| EP-4702045-A1 | GLUCOSE SENSITIVE INSULIN DERIVATIVES | Novo Nordisk A/S (DK) | 2026-03-04 | — | — | EP | disclosed |
| WO-2025016992-A1 | PHARMACEUTICAL COMPOSITIONS OF INSULIN DERIVATIVES | NOVO NORDISK A/S (DK) | 2025-01-23 | — | — | WO | disclosed |
| WO-2024223511-A1 | GLUCOSE SENSITIVE INSULIN DERIVATIVES | NOVO NORDISK A/S (DK) | 2024-10-31 | — | — | WO | disclosed |
| CN-115490709-A | KRASG12D inhibitor and application thereof in medicine | 四川海思科制药有限公司 | 2022-12-20 | — | — | CN | disclosed |
| EP-3946363-A2 | GLUCOSE SENSITIVE INSULIN DERIVATIVES | Novo Nordisk A/S (DK) | 2022-02-09 | — | — | EP | disclosed |