Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 7/20 | 0.49 |
| ▸ | NPY4R | P50391 | 7/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.49 |
| ▸ | NPY1R | P25929 | 5/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.49 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30844081 | 0.91 | MAPK8 (0.45) | MAPK8MAPK9MAPK10NPY2RNPY4R | |
| SCHEMBL29434539 | 0.87 | NMUR2 (0.56) | EPHA2NPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL31265321 | 0.84 | SLC6A2 (0.59) | EPHA2MAPK8MAPK9MAPK10NPY2R | |
| SCHEMBL30823890 | 0.84 | NPY4R (0.56) | EPHA2NPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL29993928 | 0.84 | NMUR2 (0.51) | EPHA2NPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30823901 | 0.83 | EPHA2 (0.50) | EPHA2NPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30558096 | 0.82 | SLC6A2 (0.60) | EPHA2NMUR2NMUR1 | |
| SCHEMBL31307234 | 0.81 | EPHA2 (0.61) | EPHA2NPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL31267105 | 0.81 | EPHA2 (0.55) | EPHA2NPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL31265332 | 0.81 | ACE (0.43) | EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478784-B | ENO2 monoclonal antibody 1C5, and preparation method and application thereof | 陕西脉元生物科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-114478784-A | ENO2 monoclonal antibody 1C5, and preparation method and application thereof | 陕西脉元生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |