Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.71 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.58 |
| ▸ | ITGAL | P20701 | 7/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 4/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516957 | 0.86 | ITGB2 (0.63) | TNFITGB2ICAM1ITGALALOX15 | |
| SCHEMBL28516953 | 0.86 | ITGB2 (0.63) | TNFITGB2ICAM1ITGALALOX15 | |
| SCHEMBL837864 | 0.85 | TNF (0.68) | TNFITGB2ICAM1ITGALALOX15 | |
| SCHEMBL836657 | 0.85 | TNF (0.68) | TNFITGB2ICAM1ITGALALOX15 | |
| SCHEMBL4002154 | 0.85 | TNF (0.61) | TNFITGB2ICAM1ITGALALOX15 | |
| SCHEMBL24301760 | 0.83 | TNF (0.52) | TNFITGB2ICAM1ITGALALOX15 | |
| SCHEMBL17828413 | 0.83 | TNF (1.00) | TNFITGB2ICAM1ITGALALOX15 | |
| SCHEMBL17830313 | 0.83 | TNF (1.00) | TNFITGB2ICAM1ITGALALOX15 | |
| SCHEMBL4641323 | 0.83 | TNF (0.65) | TNFITGB2ICAM1ITGALALOX15 | |
| SCHEMBL25412857 | 0.81 | ITGB2 (0.58) | TNFITGB2ICAM1ITGALALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078462-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |