SCHEMBL29530953

CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	7/20	0.57

▸	NPY1R	P25929	5/20	0.57

▸	NPY2R	P49146	3/20	0.57

▸	BACE1	P56817	3/20	0.51

▸	KISS1R	Q969F8	6/20	0.51

▸	BACE2	Q9Y5Z0	1/20	0.51

▸	NPY5R	Q15761	2/20	0.51

▸	IL1RN	P18510	1/20	0.49

▸	ERAP2	Q6P179	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29531203	1.00	NPY4R (0.57)	NPY4RNPY1RNPY2RBACE1KISS1R
SCHEMBL29403649	0.98	NPY4R (0.55)	NPY4RNPY1RNPY2RBACE1KISS1R
SCHEMBL29531366	0.98	NPY4R (0.55)	NPY4RNPY1RNPY2RBACE1KISS1R
SCHEMBL29530897	0.98	NPY4R (0.55)	NPY4RNPY1RNPY2RBACE1KISS1R
SCHEMBL29531210	0.98	NPY4R (0.55)	NPY4RNPY1RNPY2RBACE1KISS1R
SCHEMBL30184346	0.96	NPY4R (0.56)	NPY4RNPY1RNPY2RBACE1KISS1R
SCHEMBL29496461	0.95	BACE1 (0.57)	NPY4RNPY1RNPY2RBACE1KISS1R
SCHEMBL30558099	0.93	NPY1R (0.54)	NPY4RNPY1RNPY2RBACE1KISS1R
SCHEMBL29730544	0.92	NPY4R (0.58)	NPY4RNPY1RNPY2RBACE1KISS1R
SCHEMBL30184096	0.92	BACE1 (0.55)	NPY4RNPY1RNPY2RBACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12312390-B2	Rapid-acting insulin analogues of enhanced stability	CASE WESTERN RESERVE UNIVERSITY (US)	2025-05-27	—	—	US	disclosed
US-20220112262-A1	RAPID-ACTING INSULIN ANALOGUES OF ENHANCED STABILITY	CASE WESTERN RESERVE UNIVERSITY	2022-04-14	—	—	US	disclosed