Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | GRB2 | P62993 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498765 | 0.90 | CAPN1 (0.48) | SLC6A2ACERENXIAPCAPN1 | |
| SCHEMBL29530605 | 0.88 | XIAP (0.49) | SLC6A2GRB2ACERENXIAP | |
| SCHEMBL31257055 | 0.88 | CAPN1 (0.56) | SLC6A2GRB2RENXIAPCAPN1 | |
| SCHEMBL31741306 | 0.88 | GRB2 (0.49) | SLC6A2GRB2ACERENXIAP | |
| SCHEMBL30974457 | 0.86 | GRB2 (0.52) | SLC6A2GRB2ACEREN | |
| SCHEMBL31026621 | 0.86 | CAPN1 (0.52) | SLC6A2XIAPCAPN1STAT3DPP4 | |
| SCHEMBL24419898 | 0.85 | XIAP (0.54) | SLC6A2XIAPCAPN1DPP4PREP | |
| SCHEMBL34461107 | 0.85 | XIAP (0.54) | SLC6A2XIAPCAPN1DPP4PREP | |
| SCHEMBL30866244 | 0.85 | XIAP (0.54) | SLC6A2XIAPCAPN1DPP4PREP | |
| SCHEMBL30974101 | 0.85 | CALCRL (0.46) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312390-B2 | Rapid-acting insulin analogues of enhanced stability | CASE WESTERN RESERVE UNIVERSITY (US) | 2025-05-27 | — | — | US | disclosed |
| US-20220112262-A1 | RAPID-ACTING INSULIN ANALOGUES OF ENHANCED STABILITY | CASE WESTERN RESERVE UNIVERSITY | 2022-04-14 | — | — | US | disclosed |