Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 10/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375132 | 1.00 | FOLH1 (0.45) | FOLH1ERAP2BACE1BACE2CTSD | |
| SCHEMBL29939815 | 1.00 | FOLH1 (0.45) | FOLH1ERAP2BACE1BACE2CTSD | |
| SCHEMBL29393322 | 0.97 | BACE1 (0.46) | FOLH1ERAP2BACE1BACE2CTSD | |
| SCHEMBL30688995 | 0.94 | BACE1 (0.45) | FOLH1ERAP2BACE1BACE2CTSD | |
| SCHEMBL7599777 | 0.93 | ERAP2 (0.44) | FOLH1ERAP2BACE1BACE2CTSD | |
| SCHEMBL7599791 | 0.93 | ERAP2 (0.44) | FOLH1ERAP2BACE1BACE2CTSD | |
| SCHEMBL29833409 | 0.92 | ERAP2 (0.44) | FOLH1ERAP2BACE1BACE2CTSD | |
| SCHEMBL30728878 | 0.92 | MME (0.43) | — | |
| SCHEMBL30274692 | 0.92 | NAALAD2 (0.39) | FOLH1ERAP2BACE1 | |
| SCHEMBL1666827 | 0.92 | MME (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |