SCHEMBL29532003

SCHEMBL29532003

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(C)C)[C@@H](C)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 9/20 0.47
NPY1R P25929 5/20 0.47
NPY2R P49146 4/20 0.47
NPY5R Q15761 4/20 0.47
OPRM1 P35372 1/20 0.45
OPRD1 P41143 1/20 0.45
OPRK1 P41145 1/20 0.45
KEAP1 Q14145 2/20 0.44
TFPI P10646 1/20 0.44
NPBWR1 P48145 1/20 0.44
IL23R Q5VWK5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30441875 0.98 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL29808495 0.95 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL29531521 0.93 TFPI (0.45) NPY4RNPY1RNPY2RNPY5RKEAP1
SCHEMBL31696331 0.92 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29689157 0.92 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL31415957 0.91 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30148473 0.90 FURIN (0.46) NPY4RNPY1RNPY2RNPY5RTFPI
SCHEMBL26886898 0.90 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL29678407 0.90 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29967116 0.89 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3997117-A1 COMPOSITIONS AND METHODS FOR ENHANCING CELL CULTURE Life Technologies Corporation (US) 2022-05-18 EP disclosed
CN-114222813-A Compositions and methods for enhancing cell culture 生命技术公司 2022-03-22 CN disclosed