Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.46 |
| ▸ | CTSD | P07339 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | NPY4R | P50391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602869 | 1.00 | BACE1 (0.46) | BACE1CTSDNPY1RNPY2RNPY4R | |
| SCHEMBL29740735 | 0.91 | NPY1R (0.50) | NPY1RNPY2RNPY4RGSRDPP8 | |
| SCHEMBL30397735 | 0.91 | NPY1R (0.50) | NPY1RNPY2RNPY4RGSRDPP8 | |
| SCHEMBL29531457 | 0.91 | GSR (0.51) | NPY1RNPY2RNPY4RGSRDPP8 | |
| SCHEMBL8013829 | 0.91 | GSR (0.51) | NPY1RNPY2RNPY4RGSRDPP8 | |
| SCHEMBL20818872 | 0.91 | GSR (0.51) | NPY1RNPY2RNPY4RGSRDPP8 | |
| SCHEMBL9848654 | 0.90 | BACE1 (0.55) | BACE1CTSD | |
| SCHEMBL29455900 | 0.90 | NPY1R (0.46) | BACE1CTSDNPY1RNPY2RNPY4R | |
| SCHEMBL30712173 | 0.90 | ERAP2 (0.52) | BACE1CTSDNPY1RNPY2RNPY4R | |
| SCHEMBL29682467 | 0.90 | NPY4R (0.52) | NPY1RNPY2RNPY4RGSRDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |