Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.55 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374272 | 0.90 | CYP2D6 (0.53) | CYP2D6OPRL1POLBALDH1A1CHRM2 | |
| SCHEMBL11370652 | 0.84 | CYP2D6 (0.60) | CYP2D6OPRL1POLBALDH1A1CHRM2 | |
| SCHEMBL4485326 | 0.80 | OPRL1 (0.61) | CYP2D6OPRL1POLBALDH1A1CHRM2 | |
| SCHEMBL18075917 | 0.80 | CYP2D6 (0.55) | CYP2D6OPRL1POLBALDH1A1CHRM2 | |
| SCHEMBL11394628 | 0.79 | CYP2D6 (0.56) | CYP2D6OPRL1POLBALDH1A1CHRM2 | |
| SCHEMBL23316097 | 0.78 | CYP2D6 (0.53) | CYP2D6OPRL1POLBALDH1A1CHRM2 | |
| SCHEMBL29822404 | 0.78 | CHRM2 (0.51) | CYP2D6OPRL1POLBALDH1A1CHRM2 | |
| SCHEMBL17101387 | 0.78 | CHRM2 (0.51) | CYP2D6OPRL1POLBALDH1A1CHRM2 | |
| SCHEMBL1681535 | 0.78 | CYP2D6 (0.56) | CYP2D6OPRL1POLBALDH1A1CHRM2 | |
| SCHEMBL23744794 | 0.77 | OPRL1 (0.61) | CYP2D6OPRL1POLBALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759340-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2010-07-20 | — | — | US | disclosed |
| US-4255432-A | ANTIHYPERTENSIVE AGENTS, ANTIHISTAMINES, BRONCHODILATOR AGENTS, ANTIVASOSPASTIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4244961-A | 1-Oxa-3,8-diazaspiro[4.5]decan-2-ones antihypertensive agents | SYNTEX (U.S.A.) INC. (US) | 1981-01-13 | — | — | US | disclosed |