SCHEMBL29533149

SCHEMBL29533149

CC(=O)N[C@@H]1[C@@H](O[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CO)O2)[C@@H](O)[C@@H](CO)O[C@@H]1O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SELL P14151 1/20 0.62
▸ SELP P16109 1/20 0.62
▸ MAG P20916 9/20 0.59
▸ SIGLEC7 Q9Y286 6/20 0.57
▸ NANP Q8TBE9 2/20 0.51
▸ MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29425234 1.00 SELL (0.62) SELLSELPMAGSIGLEC7NANP
SCHEMBL29396615 0.95 SELP (0.62) SELLSELPMAGSIGLEC7NANP
SCHEMBL17300130 0.95 SELP (0.62) SELLSELPMAGSIGLEC7NANP
SCHEMBL29356627 0.95 SELP (0.62) SELLSELPMAGSIGLEC7NANP
SCHEMBL29532997 0.93 MAG (0.69) SELLSELPMAGSIGLEC7
SCHEMBL29392992 0.93 MAG (0.69) SELLSELPMAGSIGLEC7
SCHEMBL29581047 0.93 MAG (0.69) SELLSELPMAGSIGLEC7
SCHEMBL29460415 0.93 MAG (0.69) SELLSELPMAGSIGLEC7
SCHEMBL26491833 0.93 MAG (0.69) SELLSELPMAGSIGLEC7
SCHEMBL29432515 0.93 SELL (0.68) SELLSELPMAGSIGLEC7NANP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4326777-A1 HUMANIZED ANTI-SIALYL-TN GLYCAN ANTIBODIES AND USES THEREOF Ramot at Tel-Aviv University Ltd. (IL) 2024-02-28 — — EP disclosed
WO-2022224241-A1 CHIMERIC ANTIGEN RECEPTORS TO SIALYL-TN GLYCAN ANTIGEN RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-10-27 — — WO disclosed
WO-2022224242-A1 HUMANIZED ANTI-SIALYL-TN GLYCAN ANTIBODIES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-10-27 — — WO disclosed
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