Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.61 |
| ▸ | CD69 | Q07108 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | FGR | P09769 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22659529 | 1.00 | BTK (0.61) | BTKCD69CYP2C9CYP3A4KCNH2 | |
| SCHEMBL22659795 | 1.00 | BTK (0.61) | BTKCD69CYP2C9CYP3A4KCNH2 | |
| SCHEMBL22659454 | 1.00 | BTK (0.61) | BTKCD69CYP2C9CYP3A4KCNH2 | |
| SCHEMBL29533156 | 1.00 | BTK (0.61) | BTKCD69CYP2C9CYP3A4KCNH2 | |
| SCHEMBL29533313 | 1.00 | BTK (0.61) | BTKCD69CYP2C9CYP3A4KCNH2 | |
| SCHEMBL22659515 | 0.93 | BTK (0.62) | BTKCD69CYP2C9CYP3A4KCNH2 | |
| SCHEMBL29533265 | 0.93 | BTK (0.62) | BTKCD69CYP2C9CYP3A4KCNH2 | |
| SCHEMBL22659518 | 0.93 | BTK (0.62) | BTKCD69CYP2C9CYP3A4KCNH2 | |
| SCHEMBL22659672 | 0.93 | BTK (0.61) | BTKCD69CYP2C9CYP3A4KCNH2 | |
| SCHEMBL22659631 | 0.93 | BTK (0.61) | BTKCD69CYP2C9CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969124-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | Biogen MA Inc. (US) | 2022-03-23 | — | — | EP | disclosed |