Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29533056 | 1.00 | BTK (0.51) | BTKLCKTYK2MAP4K1ABL1 | |
| SCHEMBL29533238 | 1.00 | BTK (0.51) | BTKLCKTYK2MAP4K1ABL1 | |
| SCHEMBL29533396 | 1.00 | BTK (0.51) | BTKLCKTYK2MAP4K1ABL1 | |
| SCHEMBL29533634 | 1.00 | BTK (0.51) | BTKLCKTYK2MAP4K1ABL1 | |
| SCHEMBL22660008 | 1.00 | BTK (0.51) | BTKLCKTYK2MAP4K1ABL1 | |
| SCHEMBL22659361 | 1.00 | BTK (0.51) | BTKLCKTYK2MAP4K1ABL1 | |
| SCHEMBL22659585 | 1.00 | BTK (0.51) | BTKLCKTYK2MAP4K1ABL1 | |
| SCHEMBL22659479 | 1.00 | BTK (0.51) | BTKLCKTYK2MAP4K1ABL1 | |
| SCHEMBL22659535 | 1.00 | BTK (0.51) | BTKLCKTYK2MAP4K1ABL1 | |
| SCHEMBL22659984 | 0.93 | BTK (0.51) | BTKLCKABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969124-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | Biogen MA Inc. (US) | 2022-03-23 | — | — | EP | disclosed |