Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 20/20 | 0.67 |
| ▸ | CBLC | Q9ULV8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23002302 | 1.00 | CBLB (0.67) | CBLBCBLC | |
| SCHEMBL22695607 | 1.00 | CBLB (0.67) | CBLBCBLC | |
| SCHEMBL23002304 | 1.00 | CBLB (0.67) | CBLBCBLC | |
| SCHEMBL21200214 | 0.91 | CBLB (0.79) | CBLBCBLC | |
| SCHEMBL22695611 | 0.90 | CBLB (0.66) | CBLBCBLC | |
| SCHEMBL23002254 | 0.90 | CBLB (0.66) | CBLBCBLC | |
| SCHEMBL23002255 | 0.90 | CBLB (0.66) | CBLBCBLC | |
| SCHEMBL29535765 | 0.90 | CBLB (0.66) | CBLBCBLC | |
| SCHEMBL22695613 | 0.90 | CBLB (0.69) | CBLBCBLC | |
| SCHEMBL25246786 | 0.90 | CBLB (0.69) | CBLBCBLC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969447-A1 | CYANO CYCLOBUTYL COMPOUNDS FOR CBL-B INHIBITION AND USES THEREOF | Nurix Therapeutics, Inc. (US) | 2022-03-23 | — | — | EP | disclosed |