Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 13/20 | 0.48 |
| ▸ | ABL1 | P00519 | 6/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24285940 | 1.00 | MAP4K1 (0.48) | MAP4K1ABL1LRRK2 | |
| SCHEMBL24286064 | 0.91 | MAP4K1 (0.55) | MAP4K1ABL1LRRK2 | |
| SCHEMBL29537334 | 0.91 | MAP4K1 (0.55) | MAP4K1ABL1LRRK2 | |
| SCHEMBL29537532 | 0.87 | LRRK2 (0.43) | MAP4K1ABL1LRRK2 | |
| SCHEMBL24286082 | 0.87 | LRRK2 (0.43) | MAP4K1ABL1LRRK2 | |
| SCHEMBL24285963 | 0.84 | MAP4K1 (0.47) | MAP4K1ABL1LRRK2 | |
| SCHEMBL29537390 | 0.84 | MAP4K1 (0.47) | MAP4K1ABL1LRRK2 | |
| SCHEMBL24285961 | 0.83 | MAP4K1 (0.51) | MAP4K1ABL1LRRK2 | |
| SCHEMBL29538205 | 0.83 | MAP4K1 (0.51) | MAP4K1ABL1LRRK2 | |
| SCHEMBL24285947 | 0.83 | MAP4K1 (0.49) | MAP4K1ABL1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214207-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1st Biotherapeutics, Inc. (KR) | 2023-07-26 | — | — | EP | claimed |
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| WO-2022058890-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1ST Biotherapeutics, Inc. (KR) | 2022-03-24 | — | — | WO | claimed |