Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.40 |
| ▸ | MPO | P05164 | 6/20 | 0.38 |
| ▸ | ABL1 | P00519 | 8/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | HCK | P08631 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.36 |
| ▸ | PRKDC | P78527 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24285945 | 1.00 | LRRK2 (0.40) | LRRK2MPOABL1RIPK2PI4K2A | |
| SCHEMBL29536913 | 0.93 | LRRK2 (0.42) | LRRK2ABL1PI4K2APIK3CDEGFR | |
| SCHEMBL29537329 | 0.93 | LRRK2 (0.42) | LRRK2ABL1PI4K2APIK3CDEGFR | |
| SCHEMBL29536982 | 0.93 | LRRK2 (0.42) | LRRK2ABL1PI4K2APIK3CDEGFR | |
| SCHEMBL24285854 | 0.93 | LRRK2 (0.42) | LRRK2ABL1PI4K2APIK3CDEGFR | |
| SCHEMBL24285976 | 0.93 | LRRK2 (0.42) | LRRK2ABL1PI4K2APIK3CDEGFR | |
| SCHEMBL24286681 | 0.93 | LRRK2 (0.42) | LRRK2ABL1PI4K2APIK3CDEGFR | |
| SCHEMBL24286022 | 0.93 | LRRK2 (0.42) | LRRK2ABL1PI4K2APIK3CDEGFR | |
| SCHEMBL29537782 | 0.93 | LRRK2 (0.42) | LRRK2ABL1PI4K2APIK3CDEGFR | |
| SCHEMBL24285977 | 0.84 | LRRK2 (0.59) | LRRK2ABL1PIK3CDEGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214207-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1st Biotherapeutics, Inc. (KR) | 2023-07-26 | — | — | EP | claimed |
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| WO-2022058890-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1ST Biotherapeutics, Inc. (KR) | 2022-03-24 | — | — | WO | claimed |