Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 11/20 | 0.41 |
| ▸ | ABL1 | P00519 | 8/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24285857 | 1.00 | MAP4K1 (0.43) | MAP4K1LRRK2ABL1CHRNA7KCNH2 | |
| SCHEMBL24286659 | 0.88 | TNK2 (0.39) | MAP4K1LRRK2ABL1CDK4CDK2 | |
| SCHEMBL29537477 | 0.87 | LRRK2 (0.37) | MAP4K1LRRK2ABL1CDK4CDK2 | |
| SCHEMBL24285946 | 0.87 | LRRK2 (0.37) | MAP4K1LRRK2ABL1CDK4CDK2 | |
| SCHEMBL24286010 | 0.87 | LRRK2 (0.42) | LRRK2ABL1 | |
| SCHEMBL24286658 | 0.87 | LRRK2 (0.42) | LRRK2ABL1 | |
| SCHEMBL24286084 | 0.87 | ABL1 (0.39) | MAP4K1LRRK2ABL1 | |
| SCHEMBL24286015 | 0.87 | LRRK2 (0.42) | LRRK2ABL1 | |
| SCHEMBL24285876 | 0.87 | LRRK2 (0.42) | LRRK2ABL1 | |
| SCHEMBL29538083 | 0.87 | LRRK2 (0.42) | LRRK2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214207-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1st Biotherapeutics, Inc. (KR) | 2023-07-26 | — | — | EP | claimed |
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| WO-2022058890-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1ST Biotherapeutics, Inc. (KR) | 2022-03-24 | — | — | WO | claimed |