SCHEMBL29537799

SCHEMBL29537799

Cc1c(F)cc(N)cc1-c1ccc2nc(N)c(C(=O)[C@@H]3C[C@@H]3F)n2c1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LRRK2 Q5S007 15/20 0.60
▸ ABL1 P00519 9/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24286241 1.00 LRRK2 (0.60) LRRK2ABL1
SCHEMBL24285958 0.87 LRRK2 (0.64) LRRK2ABL1
SCHEMBL24285923 0.87 LRRK2 (0.64) LRRK2ABL1
SCHEMBL24286613 0.87 LRRK2 (0.64) LRRK2ABL1
SCHEMBL24286639 0.87 LRRK2 (0.64) LRRK2ABL1
SCHEMBL24285928 0.87 LRRK2 (0.64) LRRK2ABL1
SCHEMBL24286091 0.86 LRRK2 (0.44) LRRK2ABL1
SCHEMBL24286670 0.86 LRRK2 (0.59) LRRK2ABL1
SCHEMBL24285956 0.85 LRRK2 (0.56) LRRK2ABL1
SCHEMBL24285968 0.84 LRRK2 (0.44) LRRK2ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4214207-A1 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS 1st Biotherapeutics, Inc. (KR) 2023-07-26 — — EP claimed
CN-116457355-A 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds 第一生物治疗股份有限公司 2023-07-18 — — CN claimed
WO-2022058890-A1 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS 1ST Biotherapeutics, Inc. (KR) 2022-03-24 — — WO claimed
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