Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 14/20 | 0.77 |
| ▸ | ABL1 | P00519 | 6/20 | 0.74 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.64 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
| ▸ | BRAF | P15056 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22380055 | 1.00 | LRRK2 (0.77) | LRRK2ABL1TGFBR1MAPK13BRAF | |
| SCHEMBL25350033 | 0.92 | LRRK2 (0.78) | LRRK2ABL1 | |
| SCHEMBL22363015 | 0.88 | LRRK2 (0.72) | LRRK2ABL1 | |
| SCHEMBL22362922 | 0.87 | LRRK2 (1.00) | LRRK2ABL1 | |
| SCHEMBL22363102 | 0.85 | LRRK2 (1.00) | LRRK2ABL1 | |
| SCHEMBL22362978 | 0.84 | LRRK2 (1.00) | LRRK2ABL1 | |
| SCHEMBL22380364 | 0.84 | LRRK2 (1.00) | LRRK2ABL1 | |
| SCHEMBL22363105 | 0.84 | LRRK2 (1.00) | LRRK2ABL1 | |
| SCHEMBL22380369 | 0.84 | LRRK2 (1.00) | LRRK2ABL1 | |
| SCHEMBL22380028 | 0.84 | LRRK2 (1.00) | LRRK2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214207-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1st Biotherapeutics, Inc. (KR) | 2023-07-26 | — | — | EP | disclosed |
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022058890-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1ST Biotherapeutics, Inc. (KR) | 2022-03-24 | — | — | WO | disclosed |