Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28791203 | 1.00 | EGFR (0.59) | EGFRKDM4EALDH1A1CISD1SLC16A3 | |
| SCHEMBL20603132 | 0.86 | EGFR (0.64) | EGFRKDM4EALDH1A1CISD1SLC16A3 | |
| SCHEMBL4904127 | 0.86 | EGFR (0.64) | EGFRKDM4EALDH1A1CISD1SLC16A3 | |
| SCHEMBL4904140 | 0.86 | EGFR (0.64) | EGFRKDM4EALDH1A1CISD1SLC16A3 | |
| SCHEMBL30379853 | 0.86 | EGFR (0.64) | EGFRKDM4EALDH1A1CISD1SLC16A3 | |
| SCHEMBL23532040 | 0.80 | EGFR (0.71) | EGFRKDM4EALDH1A1CISD1SLC16A3 | |
| SCHEMBL1791408 | 0.80 | EGFR (0.71) | EGFRKDM4EALDH1A1CISD1SLC16A3 | |
| SCHEMBL1791407 | 0.80 | EGFR (0.71) | EGFRKDM4EALDH1A1CISD1SLC16A3 | |
| SCHEMBL20603136 | 0.79 | EGFR (0.56) | EGFRKDM4EALDH1A1CISD1SLC16A3 | |
| SCHEMBL30379788 | 0.79 | EGFR (0.56) | EGFRKDM4EALDH1A1CISD1SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507158-B | Pleuromutilin alpha-cyano cinnamic acid ester compounds with drug-resistant bacteria resisting activity and preparation method and application thereof | 广东医科大学附属医院 | 2023-04-28 | — | — | CN | disclosed |
| CN-114507158-A | Pleuromutilin alpha-cyano cinnamate compounds with drug-resistant bacterium resisting activity and preparation method and application thereof | 广东医科大学附属医院 | 2022-05-17 | — | — | CN | disclosed |