Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 6/20 | 0.37 |
| ▸ | KLK7 | P49862 | 4/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.34 |
| ▸ | AHCY | P23526 | 2/20 | 0.33 |
| ▸ | MARS1 | P56192 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | CHAT | P28329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744295 | 0.90 | KLK7 (0.46) | DOT1LKLK7KLK5PLA2G2AAHCY | |
| SCHEMBL16287975 | 0.80 | CHAT (0.40) | CHAT | |
| SCHEMBL16287982 | 0.80 | CHAT (0.40) | CHAT | |
| SCHEMBL16288001 | 0.80 | CHAT (0.40) | CHAT | |
| SCHEMBL27222172 | 0.80 | CHAT (0.40) | CHAT | |
| SCHEMBL17991817 | 0.80 | CHAT (0.40) | CHAT | |
| SCHEMBL16287990 | 0.80 | CHAT (0.40) | CHAT | |
| SCHEMBL30744230 | 0.79 | DOT1L (0.46) | DOT1LPLA2G2AAHCYMARS1PRKACA | |
| SCHEMBL16574734 | 0.79 | CHAT (0.36) | CHAT | |
| SCHEMBL23056445 | 0.77 | CACNA1B (0.36) | KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974563-A1 | CYCLIC PEPTIDES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2022-03-30 | — | — | EP | disclosed |