SCHEMBL29540150

SCHEMBL29540150

CSCC[C@H](N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 17/20 0.44
▸ FNTB P49356 17/20 0.44
▸ PGGT1B P53609 13/20 0.44
▸ NPY4R P50391 3/20 0.41
▸ NPY1R P25929 2/20 0.41
▸ NPY2R P49146 2/20 0.41
▸ NPY5R Q15761 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29985357 1.00 FNTA (0.44) FNTAFNTBPGGT1BNPY4RNPY1R
SCHEMBL29527234 0.91 FNTA (0.51) FNTAFNTBPGGT1BNPY4RNPY1R
SCHEMBL29789057 0.89 NPY4R (0.50) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30761725 0.89 FNTA (0.49) FNTAFNTBPGGT1BNPY4RNPY1R
SCHEMBL31643025 0.88 FNTA (0.49) FNTAFNTBPGGT1B
SCHEMBL30479333 0.88 FNTA (0.51) FNTAFNTBPGGT1BNPY4RNPY1R
SCHEMBL30567411 0.87 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5R
SCHEMBL31314418 0.87 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30117177 0.87 PDCD1LG2 (0.42) NPY4RNPY1RNPY2RNPY5R
SCHEMBL9189133 0.87 FNTA (0.54) FNTAFNTBPGGT1BNPY4RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 — — US disclosed
US-11891457-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 — — US disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891457-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R FNTA 445/4885FNTB 837/4885PGGT1B 2074/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R FNTA 445/4885FNTB 837/4885PGGT1B 2074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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