SCHEMBL29540171

SCHEMBL29540171

C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 9/20 0.64
▸ KISS1R Q969F8 7/20 0.61
▸ GLP1R P43220 1/20 0.59
▸ GCGR P47871 1/20 0.59
▸ GIPR P48546 1/20 0.59
▸ NPBWR1 P48145 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29540457 0.92 GLP1R (0.63) IL23RKISS1RGLP1RGCGRGIPR
SCHEMBL34467247 0.91 IL23R (0.64) IL23RKISS1R
SCHEMBL30299216 0.90 GLP1R (0.65) IL23RKISS1RGLP1RGCGRGIPR
SCHEMBL30712879 0.89 GLP1R (0.62) IL23RGLP1RGCGRGIPR
SCHEMBL11596073 0.88 IL23R (0.66) IL23R
SCHEMBL11490971 0.88 IL23R (0.66) IL23R
SCHEMBL11596064 0.88 IL23R (0.66) IL23R
SCHEMBL11420342 0.88 IL23R (0.66) IL23R
SCHEMBL11420357 0.88 IL23R (0.66) IL23R
SCHEMBL11490981 0.88 IL23R (0.66) IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 — — US disclosed
US-11891457-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 — — US disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891457-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R IL23R 3167/4885KISS1R 193/4885GLP1R 3/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R IL23R 3167/4885KISS1R 193/4885GLP1R 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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