Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398313 | 1.00 | MDM4 (0.58) | MDM4TP53KMT2AMDM2CASP3 | |
| SCHEMBL16095188 | 1.00 | MDM4 (0.58) | MDM4TP53KMT2AMDM2CASP3 | |
| SCHEMBL29398093 | 1.00 | MDM4 (0.58) | MDM4TP53KMT2AMDM2CASP3 | |
| SCHEMBL16095190 | 1.00 | MDM4 (0.58) | MDM4TP53KMT2AMDM2CASP3 | |
| Hydrochloric Acid SCHEMBL25358848 | 0.99 | MDM4 (0.57) | MDM4TP53KMT2AMDM2CASP3 | |
| Hydrochloric Acid SCHEMBL30585413 | 0.99 | MDM4 (0.57) | MDM4TP53KMT2AMDM2CASP3 | |
| Hydrochloric Acid SCHEMBL25358854 | 0.99 | MDM4 (0.57) | MDM4TP53KMT2AMDM2CASP3 | |
| Trifluoroacetic Acid SCHEMBL4363443 | 0.94 | MDM2 (0.54) | MDM4TP53KMT2AMDM2CASP3 | |
| SCHEMBL31317450 | 0.93 | MDM2 (0.57) | MDM4TP53KMT2AMDM2CASP3 | |
| SCHEMBL21315799 | 0.93 | MDM2 (0.57) | MDM4TP53KMT2AMDM2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118510549-A | Nanoparticle pharmaceutical compositions with reduced nanoparticle size and improved polydispersity index | 圣诺制药公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118475371-A | Improved nanoparticle formulations based on histidine-lysine copolymer formation | 圣诺制药公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-116367841-A | Nucleoside-containing siRNA for treating viral diseases | 圣诺制药公司 | 2023-06-30 | — | — | CN | disclosed |
| EP-4196102-A1 | NUCLEOSIDE CONTAINING siRNAS FOR TREATING VIRAL DISEASES | Sirnaomics, Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022072950-A1 | NUCLEOSIDE CONTAINING siRNAS FOR TREAT VIRAL DISEASES | SIRNAOMICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |