SCHEMBL29542492

SCHEMBL29542492

CN1CCC(c2cccc(N(C)c3ccc(Oc4nc(O)c5ccncc5n4)cc3)c2)CC1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17891443 1.00 KDM4C (0.54) KDM4C
SCHEMBL17898278 0.91 KDM4C (0.55) KDM4C
SCHEMBL17602049 0.88 KDM4C (0.69) KDM4C
SCHEMBL30139687 0.88 KDM4C (0.69) KDM4C
SCHEMBL29541985 0.84 KDM4C (0.68) KDM4C
SCHEMBL17602100 0.84 KDM4C (0.68) KDM4C
SCHEMBL17602230 0.84 KDM4C (0.63) KDM4C
SCHEMBL17898270 0.83 KDM4C (0.45) KDM4C
SCHEMBL17602119 0.83 KDM4C (0.69) KDM4C
SCHEMBL29542310 0.83 KDM4C (0.69) KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3430008-B1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RES INC (US) 2022-05-18 — — EP disclosed
Send feedback