⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008115 | 0.85 | — | — | |
| SCHEMBL10071602 | 0.85 | — | — | |
| SCHEMBL10071604 | 0.81 | — | — | |
| SCHEMBL10071613 | 0.81 | — | — | |
| SCHEMBL10071603 | 0.81 | — | — | |
| SCHEMBL22922999 | 0.79 | MEN1 (0.38) | — | |
| SCHEMBL6536753 | 0.68 | — | — | |
| SCHEMBL22015781 | 0.68 | — | — | |
| SCHEMBL10071612 | 0.67 | MEN1 (0.32) | — | |
| SCHEMBL10071585 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847117-B2 | Process for preparing alkyl(methoxymethyl)trimethylsilanylmethylamines | WACKER CHEMIE AG (DE) | 2010-12-07 | — | — | US | disclosed |
| EP-2050754-B1 | Method for manufacturing alkyl-methoxymethyl-trimethylsilanylmethyl amines | WACKER CHEMIE AG (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-2190840-A2 | CHEMICAL COMPOUNDS 979 | AstraZeneca AB (SE) | 2010-06-02 | — | — | EP | disclosed |
| EP-2050754-A1 | Method for manufacturing alkyl-methoxymethyl-trimethylsilanylmethyl amines | Wacker Chemie AG (DE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2009024821-A2 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |
| US-20090036700-A1 | Process For Preparing Alkyl(Methoxymethyl)Trimethylsilanylmethylamines | WACKER CHEMIE AG (DE) | 2009-02-05 | — | — | US | disclosed |