Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545188 | 0.76 | PRKD1 (0.44) | KDM4ENTRK1ALDH1A1SMN1; SMN2MAPK10 | |
| SCHEMBL29545106 | 0.76 | PIK3C3 (0.42) | KDM4ENTRK1CDK9GSK3ACDK5 | |
| SCHEMBL29544729 | 0.72 | NTRK1 (0.36) | KDM4ENTRK1CDK9GSK3ACDK5 | |
| SCHEMBL16798235 | 0.70 | MAPK1 (0.46) | — | |
| SCHEMBL29544683 | 0.70 | MAPK10 (0.39) | KDM4ENTRK1MEN1KMT2AMAPK10 | |
| SCHEMBL16264725 | 0.68 | JAK2 (0.45) | KDM4ECDK9GSK3ACDK5TAOK1 | |
| SCHEMBL16397524 | 0.68 | — | — | |
| SCHEMBL30477820 | 0.68 | — | — | |
| SCHEMBL20865890 | 0.68 | NTRK1 (0.48) | KDM4ENTRK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14850280 | 0.67 | SYK (0.51) | KDM4EKDM4AKDM5CKDM4CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |