Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 15/20 | 0.64 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.63 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.63 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20733901 | 1.00 | FGFR4 (0.64) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL20733960 | 0.93 | FGFR1 (0.66) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL29545954 | 0.93 | FGFR1 (0.66) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL29546327 | 0.90 | FGFR4 (0.57) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL20487744 | 0.89 | FGFR1 (0.79) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL29886189 | 0.89 | FGFR1 (0.79) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL29545560 | 0.87 | FGFR1 (0.59) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL20734014 | 0.87 | FGFR1 (0.66) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL29545461 | 0.87 | FGFR1 (0.66) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL20733970 | 0.85 | FGFR1 (0.72) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384790-B | Fibroblast growth factor receptor inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-05-10 | — | — | CN | disclosed |