Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 4/20 | 0.43 |
| ▸ | CFD | P00746 | 11/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545357 | 1.00 | HPGD (0.43) | HPGDCTSCCFDSLC6A2SLC6A4 | |
| SCHEMBL17047371 | 1.00 | HPGD (0.43) | HPGDCTSCCFDSLC6A2SLC6A4 | |
| SCHEMBL17024747 | 1.00 | HPGD (0.43) | HPGDCTSCCFDSLC6A2SLC6A4 | |
| SCHEMBL18578316 | 1.00 | HPGD (0.43) | HPGDCTSCCFDSLC6A2SLC6A4 | |
| SCHEMBL29544919 | 1.00 | HPGD (0.43) | HPGDCTSCCFDSLC6A2SLC6A4 | |
| SCHEMBL20687453 | 1.00 | HPGD (0.43) | HPGDCTSCCFDSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL17023478 | 0.99 | CTSC (0.42) | HPGDCTSCCFDSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL18553939 | 0.99 | CTSC (0.42) | HPGDCTSCCFDSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL29545772 | 0.99 | CTSC (0.42) | HPGDCTSCCFDSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL29545413 | 0.99 | CTSC (0.42) | HPGDCTSCCFDSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756881-A | Targeting complement factor D degradation agent and preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| EP-4125914-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| CN-115427044-A | Pyrrolopyrimidines as complement inhibitors | 拜奥克里斯特制药公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115066438-A | ASGPR binding compounds for degrading extracellular proteins | 阿维拉治疗公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |