Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 3/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18591145 | 1.00 | GRK2 (0.49) | GRK2CASP6CASP8CTDSP1TDP1 | |
| Hydrochloric Acid SCHEMBL18554739 | 0.99 | GRK2 (0.48) | GRK2CASP6CASP8CTDSP1TDP1 | |
| SCHEMBL29340506 | 0.84 | GRK2 (0.49) | GRK2CASP6CASP8CTDSP1TDP1 | |
| SCHEMBL29840719 | 0.84 | MEN1 (0.50) | TGM2MEN1NPC1LMNARAB9A | |
| SCHEMBL18591149 | 0.84 | MEN1 (0.50) | TGM2MEN1NPC1LMNARAB9A | |
| SCHEMBL31148140 | 0.83 | CTSC (0.43) | TGM2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30945059 | 0.83 | DPP4 (0.54) | TDP1L3MBTL1GAATGM2MEN1 | |
| Hydrochloric Acid SCHEMBL18578488 | 0.83 | MEN1 (0.49) | TGM2MEN1NPC1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL31148064 | 0.82 | CTSC (0.42) | TGM2MEN1KMT2ACTSCDPP4 | |
| SCHEMBL20296977 | 0.82 | EPHX2 (0.44) | CTSCUBE2MDCUN1D1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4053117-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2022-09-07 | — | — | EP | claimed |
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |