Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 1.00 |
| ▸ | CTSD | P07339 | 18/20 | 1.00 |
| ▸ | BACE2 | Q9Y5Z0 | 18/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222560 | 1.00 | BACE1 (1.00) | BACE1CTSDBACE2CYP3A4CYP2D6 | |
| SCHEMBL5218529 | 0.98 | BACE1 (0.96) | BACE1CTSDBACE2CYP3A4CYP2D6 | |
| SCHEMBL5222574 | 0.93 | BACE1 (0.88) | BACE1CTSDBACE2CYP3A4CYP2D6 | |
| SCHEMBL5222568 | 0.93 | BACE1 (0.88) | BACE1CTSDBACE2CYP3A4CYP2D6 | |
| SCHEMBL5218279 | 0.93 | BACE1 (0.86) | BACE1CTSDBACE2CYP3A4CYP2D6 | |
| SCHEMBL5223879 | 0.92 | BACE1 (0.85) | BACE1CTSDBACE2CYP3A4CYP2D6 | |
| SCHEMBL5220661 | 0.91 | BACE1 (0.84) | BACE1CTSDBACE2CYP3A4CYP2D6 | |
| SCHEMBL5218524 | 0.91 | BACE1 (0.84) | BACE1CTSDBACE2CYP3A4CYP2D6 | |
| SCHEMBL5222003 | 0.91 | BACE1 (0.84) | BACE1CTSDBACE2CYP3A4CYP2D6 | |
| Formic Acid SCHEMBL5380297 | 0.91 | BACE1 (0.83) | BACE1CTSDBACE2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025032158-A1 | METHOD TO TREAT TAUOPATHIES | Institut National de la Santé et de la Recherche Médicale (FR) | 2025-02-13 | — | — | WO | disclosed |
| CN-109953991-B | Use of gelsmin for treating diseases or disorders associated with amyloid deposition and/or tauopathy | 福建医科大学 | 2022-05-10 | — | — | CN | disclosed |