Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 12/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120952 | 1.00 | CRBN (0.40) | CRBNTNFDDB1BRD9MAPT | |
| SCHEMBL29547332 | 0.87 | BRD9 (0.42) | CRBNDDB1BRD9MAPT | |
| SCHEMBL20121003 | 0.87 | BRD9 (0.42) | CRBNDDB1BRD9MAPT | |
| SCHEMBL20120540 | 0.86 | DDB1 (0.42) | CRBNDDB1BRD9MAPT | |
| SCHEMBL29548268 | 0.86 | DDB1 (0.42) | CRBNDDB1BRD9MAPT | |
| SCHEMBL20120834 | 0.85 | BRD9 (0.48) | BRD9MAPT | |
| SCHEMBL27099257 | 0.85 | BRD9 (0.48) | BRD9MAPT | |
| SCHEMBL29547543 | 0.85 | BRD9 (0.48) | BRD9MAPT | |
| SCHEMBL27098486 | 0.85 | BRD9 (0.48) | BRD9MAPT | |
| SCHEMBL27098526 | 0.83 | BRD9 (0.46) | BRD9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-3999182-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |