Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489345 | 1.00 | DHODH (0.49) | DHODHSLC6A9MEN1KMT2ARAB9A | |
| SCHEMBL8606601 | 0.86 | DHODH (0.45) | DHODHMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8212071 | 0.84 | DHODH (0.46) | DHODHSLC6A9MEN1KMT2ARAB9A | |
| SCHEMBL8888473 | 0.84 | DHODH (0.36) | DHODHMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8493385 | 0.84 | DHODH (0.43) | DHODHMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8891126 | 0.84 | DHODH (0.41) | DHODHSLC6A9MEN1KMT2ARAB9A | |
| SCHEMBL8891934 | 0.84 | DHODH (0.41) | DHODHSLC6A9MEN1KMT2ARAB9A | |
| SCHEMBL8492364 | 0.83 | HPGD (0.37) | DHODHMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL7573020 | 0.83 | DHODH (0.47) | DHODHMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8494851 | 0.83 | DHODH (0.53) | DHODHMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553586-B | Preparation method of herbicide isoxaflutole key intermediate | 南京正荣医药化学有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-115745905-B | Synthetic method of isoxaflutole and intermediate thereof | 安徽宁亿泰科技有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-115745905-A | Synthesis method of isoxaflutole and intermediate thereof | 安徽宁亿泰科技有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-111848469-B | Isoxazole herbicide intermediate and preparation method thereof | 帕潘纳(北京)科技有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-109553586-B | Preparation method of herbicide isoxaflutole key intermediate | 南京正荣医药化学有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-109553586-B | Preparation method of herbicide isoxaflutole key intermediate | 南京正荣医药化学有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-114456095-A | Preparation method of isoxazole compound and intermediate thereof | 北京颖泰嘉和生物科技股份有限公司 | 2022-05-10 | — | — | CN | disclosed |