Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 15/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120780 | 1.00 | BRD9 (0.45) | BRD9CRBNITKALKEGFR | |
| SCHEMBL29547818 | 0.94 | BRD9 (0.47) | BRD9CRBNEGFR | |
| SCHEMBL20120798 | 0.94 | BRD9 (0.47) | BRD9CRBNEGFR | |
| SCHEMBL22906737 | 0.94 | BRD9 (0.40) | BRD9CRBNITKALKEGFR | |
| SCHEMBL20120621 | 0.93 | BRD9 (0.45) | BRD9CRBNEGFR | |
| SCHEMBL29547622 | 0.93 | BRD9 (0.45) | BRD9CRBNEGFR | |
| SCHEMBL20120605 | 0.90 | BRD9 (0.42) | BRD9CRBNITK | |
| SCHEMBL30302377 | 0.90 | BRD9 (0.42) | BRD9CRBNITK | |
| SCHEMBL20120604 | 0.90 | BRD9 (0.42) | BRD9CRBNITK | |
| SCHEMBL20133038 | 0.89 | BRD9 (0.47) | BRD9CRBNEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999182-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |