Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | CCR1 | P32246 | 3/20 | 0.74 |
| ▸ | CCR5 | P51681 | 3/20 | 0.74 |
| ▸ | CCR8 | P51685 | 3/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | METAP1 | P53582 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.74 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.74 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | TP53 | P04637 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL29783031 | 1.00 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL16950075 | 1.00 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL3713644 | 0.97 | KDM4E (0.78) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL17351671 | 0.95 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL16758697 | 0.95 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL17351682 | 0.95 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL16758690 | 0.95 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL7909768 | 0.93 | KDM4E (0.64) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL6911813 | 0.90 | KDM4E (0.67) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL9638434 | 0.89 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192222-A | Method for synthesizing bryoid C-ring fragment key intermediate and C-ring fragment | 四川大学 | 2024-12-27 | — | — | CN | claimed |
| CN-118878387-A | Preparation method and application of alpha-arene-alpha-trifluoromethyl alcohol compound | 遵义医科大学 | 2024-11-01 | — | — | CN | claimed |
| CN-118307410-A | Preparation method of chiral secondary alcohol compound | 武汉大学 | 2024-07-09 | — | — | CN | claimed |
| CN-117486836-A | Preparation method of 2-aryl-3-carbonyl substituted tetrahydrofuran and tetrahydropyran compound | 遵义医科大学 | 2024-02-02 | — | — | CN | claimed |
| CN-117024312-A | Aryl sulfonyl fluoride and preparation method using aryl sulfonium salt as substrate | 上海应用技术大学 | 2023-11-10 | — | — | CN | claimed |
| CN-114605237-A | Preparation method and application of fluoroalkyl ketone compound | 武汉大学 | 2022-06-10 | — | — | CN | claimed |
| CN-114456206-A | Alpha-fluoroalkyl substituted cyclopropenyl ether (alcohol), preparation method and application thereof | 武汉大学 | 2022-05-10 | — | — | CN | claimed |
| CN-114456134-A | Alpha-fluoroalkyl substituted cyclopropyl alcohol compound, and preparation method and application thereof | 武汉大学 | 2022-05-10 | — | — | CN | claimed |
| CN-119219467-A | Benzodifluoro cyclohexane bridged ring compound, preparation method and application thereof | 武汉大学 | 2024-12-31 | — | — | CN | disclosed |
| CN-119219466-A | Difluoro cyclobutane parallel ring compound, preparation method and application thereof | 武汉大学 | 2024-12-31 | — | — | CN | disclosed |
| CN-119192222-A | Method for synthesizing bryoid C-ring fragment key intermediate and C-ring fragment | 四川大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-118878387-A | Preparation method and application of alpha-arene-alpha-trifluoromethyl alcohol compound | 遵义医科大学 | 2024-11-01 | — | — | CN | disclosed |
| CN-114456134-B | Alpha-fluoroalkyl substituted cyclopropyl alcohol compound, and preparation method and application thereof | 武汉大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117486836-A | Preparation method of 2-aryl-3-carbonyl substituted tetrahydrofuran and tetrahydropyran compound | 遵义医科大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-117024312-A | Aryl sulfonyl fluoride and preparation method using aryl sulfonium salt as substrate | 上海应用技术大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-116217395-A | Preparation method of beta-carbonyl compound | 黄淮学院 | 2023-06-06 | — | — | CN | disclosed |
| CN-114605237-B | Preparation method and application of fluoroalkyl ketone compound | 武汉大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-114605237-A | Preparation method and application of fluoroalkyl ketone compound | 武汉大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-114456206-A | Alpha-fluoroalkyl substituted cyclopropenyl ether (alcohol), preparation method and application thereof | 武汉大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-114456134-A | Alpha-fluoroalkyl substituted cyclopropyl alcohol compound, and preparation method and application thereof | 武汉大学 | 2022-05-10 | — | — | CN | disclosed |