Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 10/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | NMBR | P28336 | 3/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548267 | 0.93 | F9 (0.40) | F9TACR1SIRT1CFTRNMBR | |
| SCHEMBL17999520 | 0.92 | F9 (0.42) | F9TACR1CFTRNMBRGHSR | |
| SCHEMBL17999521 | 0.92 | F9 (0.42) | F9TACR1CFTRNMBRGHSR | |
| SCHEMBL17999310 | 0.90 | TACR1 (0.43) | F9TACR1CFTRNMBRGHSR | |
| SCHEMBL17999311 | 0.90 | TACR1 (0.43) | F9TACR1CFTRNMBRGHSR | |
| SCHEMBL17999457 | 0.87 | F9 (0.45) | F9TACR1SIRT1CFTRNMBR | |
| SCHEMBL29547959 | 0.84 | TACR1 (0.38) | F9TACR1NMBRGHSR | |
| SCHEMBL17999464 | 0.79 | F9 (0.45) | F9TACR1SIRT1CFTRNMBR | |
| SCHEMBL5881032 | 0.79 | TACR1 (0.51) | TACR1NMBRGHSRLMNABAZ2B | |
| SCHEMBL17999559 | 0.70 | F9 (0.41) | F9TACR1NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3258929-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-04-27 | — | — | EP | disclosed |