Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.61 |
| ▸ | WIZ | O95785 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27097903 | 1.00 | CRBN (0.61) | CRBNWIZ | |
| SCHEMBL29547363 | 0.92 | CRBN (0.57) | CRBNWIZ | |
| SCHEMBL22907254 | 0.92 | CRBN (0.57) | CRBNWIZ | |
| SCHEMBL22297051 | 0.84 | CRBN (0.61) | CRBNWIZ | |
| SCHEMBL20120664 | 0.84 | CRBN (0.61) | CRBNWIZ | |
| SCHEMBL27139685 | 0.84 | CRBN (0.67) | CRBNWIZ | |
| SCHEMBL20120416 | 0.83 | CRBN (0.55) | CRBN | |
| SCHEMBL20760056 | 0.83 | CRBN (0.72) | CRBN | |
| SCHEMBL20234563 | 0.81 | CRBN (0.66) | CRBNWIZ | |
| SCHEMBL30007020 | 0.81 | CRBN (0.66) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| EP-3999182-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |