Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25130446 | 0.91 | AKT1 (0.45) | AKT1PLK1CAPN1MGLLHDAC3 | |
| SCHEMBL23451321 | 0.91 | AKT1 (0.45) | AKT1PLK1CAPN1MGLLHDAC3 | |
| SCHEMBL25330704 | 0.89 | AKT1 (0.40) | AKT1HPGDHTTSMN1; SMN2PLK1 | |
| SCHEMBL29467661 | 0.89 | GLP1R (0.43) | AKT1HPGDHTTSMN1; SMN2PLK1 | |
| SCHEMBL25332401 | 0.86 | GLP1R (0.41) | AKT1HPGDHTTSMN1; SMN2PLK1 | |
| SCHEMBL29467572 | 0.86 | GLP1R (0.41) | AKT1HPGDHTTSMN1; SMN2PLK1 | |
| SCHEMBL29548331 | 0.86 | HPGD (0.36) | HPGDHTTSMN1; SMN2MGLLMAPT | |
| SCHEMBL23451337 | 0.86 | AKT1 (0.46) | AKT1PLK1CAPN1ELANEPTGS1 | |
| SCHEMBL31690588 | 0.85 | AKT1 (0.42) | AKT1HPGDHTTSMN1; SMN2PLK1 | |
| SCHEMBL24872427 | 0.85 | AKT1 (0.40) | AKT1SMN1; SMN2CAPN1TLR2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986463-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2022-04-27 | — | — | EP | disclosed |