Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642391 | 1.00 | TTR (0.50) | TTRLOXL2HTR1AHTR7HTR6 | |
| SCHEMBL19642392 | 1.00 | TTR (0.50) | TTRLOXL2HTR1AHTR7HTR6 | |
| SCHEMBL19662313 | 0.94 | TTR (0.52) | TTRLOXL2HTR1AHTR7HTR6 | |
| SCHEMBL19641740 | 0.94 | TTR (0.52) | TTRLOXL2HTR1AHTR7HTR6 | |
| SCHEMBL19642366 | 0.94 | TTR (0.52) | TTRLOXL2HTR1AHTR7HTR6 | |
| SCHEMBL19642442 | 0.88 | TTR (0.54) | TTR | |
| SCHEMBL29547891 | 0.88 | TTR (0.54) | TTR | |
| SCHEMBL19642379 | 0.85 | TTR (0.56) | TTRHTR1AHTR7HTR6MAOA | |
| SCHEMBL19642435 | 0.83 | NOTUM (0.56) | TTR | |
| SCHEMBL19662117 | 0.83 | NOTUM (0.56) | TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | disclosed |