Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB3 | P54753 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25044276 | 0.79 | — | — | |
| SCHEMBL13680762 | 0.79 | EPHB3 (0.42) | EPHB3CSNK1A1CSNK1DCSNK1EMAPK14 | |
| SCHEMBL18307739 | 0.77 | EPHB3 (0.39) | EPHB3CSNK1A1CSNK1DCSNK1EMAPK14 | |
| SCHEMBL22491181 | 0.76 | AHR (0.33) | — | |
| SCHEMBL23104609 | 0.76 | MAPK14 (0.35) | MAPK14KDR | |
| SCHEMBL23121172 | 0.76 | EPHB3 (0.46) | EPHB3MAPK14KDR | |
| SCHEMBL23089448 | 0.76 | EPHB3 (0.40) | EPHB3CSNK1A1CSNK1DCSNK1EMAPK14 | |
| SCHEMBL23425908 | 0.73 | EPHB3 (0.42) | EPHB3CSNK1A1CSNK1DCSNK1EMAPK14 | |
| SCHEMBL23109050 | 0.73 | EPHB3 (0.39) | EPHB3CSNK1A1CSNK1DCSNK1EMAPK14 | |
| SCHEMBL22726968 | 0.73 | MAP4K4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |