Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB3 | P54753 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.32 |
| ▸ | YAP1 | P46937 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29548260 | 0.82 | EPHB3 (0.43) | EPHB3MCHR1HRH3PIM1PIM2 | |
| SCHEMBL29548529 | 0.81 | EPHB3 (0.42) | EPHB3MCHR1HRH3GHSRKCNH2 | |
| SCHEMBL29548264 | 0.80 | EPHB3 (0.45) | EPHB3MCHR1HRH3HTR3AKCNH2 | |
| SCHEMBL29548191 | 0.79 | EPHB3 (0.39) | EPHB3MCHR1HRH3KCNH2GRIN1 | |
| SCHEMBL29548130 | 0.77 | EPHB3 (0.46) | EPHB3MCHR1HRH3KCNH2GRIN1 | |
| SCHEMBL29548553 | 0.76 | EPHB3 (0.48) | EPHB3MCHR1HRH3KCNH2GRIN1 | |
| SCHEMBL29548232 | 0.75 | EPHB3 (0.43) | EPHB3MCHR1HRH3KCNH2 | |
| SCHEMBL29548380 | 0.75 | EPHB3 (0.47) | EPHB3MCHR1HRH3KCNH2MAOA | |
| SCHEMBL29548184 | 0.75 | EPHB3 (0.47) | EPHB3MCHR1HRH3KCNH2MAOA | |
| SCHEMBL29548854 | 0.74 | EPHB3 (0.48) | EPHB3MCHR1HRH3KCNH2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |