Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.62 |
| ▸ | EP300 | Q09472 | 2/20 | 0.54 |
| ▸ | BRD2 | P25440 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | TSPO | P30536 | 1/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.51 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720367 | 0.89 | BRD4 (0.65) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL29548942 | 0.89 | BRD4 (0.65) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL15558963 | 0.84 | BRD4 (0.61) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL28720352 | 0.84 | BRD4 (0.59) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL28720341 | 0.84 | BRD4 (0.60) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL29548931 | 0.84 | BRD4 (0.60) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL28721245 | 0.84 | BRD4 (0.60) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL29548574 | 0.84 | BRD4 (0.60) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL28721211 | 0.84 | BRD4 (0.60) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL29549256 | 0.84 | BRD4 (0.60) | BRD4EP300BRD2ADORA2BTSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041253-B | Pyridine N-oxide derivative and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-03-29 | — | — | CN | disclosed |