SCHEMBL29548812

SCHEMBL29548812

FC(F)C(Cl)=CC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22501477 1.00
SCHEMBL22501894 1.00
SCHEMBL31062661 0.77
SCHEMBL1615572 0.67
SCHEMBL2323939 0.67
SCHEMBL26898 0.67
SCHEMBL26899 0.67
SCHEMBL16097089 0.65
SCHEMBL22686765 0.65
SCHEMBL1221565 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630687-B2 Compositions comprising Z-1,1,1,4,4,4-hexafluoro-2-butene and uses thereof THE CHEMOURS COMPANY FC, LLC (US) 2026-05-19 US disclosed
US-20260042721-A1 PROCESS FOR PRODUCING 1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE THE CHEMOURS COMPANY FC, LLC (US) 2026-02-12 US disclosed
US-12421181-B2 Process for producing 1,1,1,4,4,4-hexafluorobut-2-ene THE CHEMOURS COMPANY FC, LLC (US) 2025-09-23 US disclosed
US-12421180-B2 Processes for producing Z-1,1,1,4,4,4-hexafluorobut-2-ene and intermediates for producing same THE CHEMOURS COMPANY FC, LLC (US) 2025-09-23 US disclosed
EP-4083164-B1 COMPOSITIONS COMPRISING Z-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE AND USES THEREOF CHEMOURS CO FC LLC (US) 2025-04-09 EP disclosed
EP-3947326-B1 PROCESSES FOR PRODUCING Z-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE AND INTERMEDIATES FOR PRODUCING SAME CHEMOURS CO FC LLC (US) 2025-01-15 EP disclosed
CN-113661156-B Process for the preparation of 1, 4-hexafluorobut-2-ene 科慕埃弗西有限公司 2024-11-26 CN disclosed
US-12037475-B2 Compositions comprising Z-1, 1, 1,4,4,4-hexafluoro-2-butene and uses thereof THE CHEMOURS COMPANY FC, LLC (US) 2024-07-16 US disclosed
US-20240199833-A1 COMPOSITIONS COMPRISING Z-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2024-06-20 US disclosed
EP-4083164-A1 COMPOSITIONS COMPRISING Z-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE AND USES THEREOF The Chemours Company FC, LLC (US) 2022-11-02 EP disclosed
US-20220194882-A1 PROCESSES FOR PRODUCING Z-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE AND INTERMEDIATES FOR PRODUCING SAME THE CHEMOURS COMPANY FC, LLC (US) 2022-06-23 US disclosed
EP-3253844-B1 COMPOSITIONS COMPRISING Z-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE AND USES THEREOF CHEMOURS CO FC LLC (US) 2022-06-22 EP disclosed
US-20220162141-A1 PROCESS FOR PRODUCING 1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE THE CHEMOURS COMPANY FC, LLC (US) 2022-05-26 US disclosed