Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800636 | 0.80 | MAPT (0.68) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL6419561 | 0.72 | MAPT (0.53) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL5815648 | 0.72 | NPC1 (0.74) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL13549798 | 0.72 | NPC1 (0.74) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL5815653 | 0.72 | NPC1 (0.74) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL6714010 | 0.72 | MAPT (0.67) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL7626803 | 0.71 | MAPT (0.67) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL7626806 | 0.71 | MAPT (0.67) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL19936663 | 0.71 | MAPT (0.70) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL6413690 | 0.70 | MAPT (0.51) | MAPTKMT2AMEN1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986634-A1 | SIZED MOLDS OBTAINABLE FROM A MOLDING MATERIAL MIXTURE CONTAINING AN INORGANIC BONDING AGENT AND PHOSPHATIC COMPOUNDS AND OXIDIC BORON COMPOUNDS AND METHOD FOR PRODUCTION AND USE THEREOF | ASK Chemicals GmbH (DE) | 2022-04-27 | — | — | EP | disclosed |